[Linus Pauling Virtual Exhibit]

Answers to Frequently Asked Questions about the Pauling Therapy for Heart Disease

O. Fonorow
M. S. Till
Intelisoft Multimedia
Originally posted: 12-08-2000
Last Updated: Thu Jan 24 08:45:32 CST 2002
  1. How much vitamin C and lysine should I take?
  2. If Pauling really said this was the cure for coronary heart disease, why haven't I heard about it?
  3. I heard that Mathias Rath calls vitamin C the cure but Pauling never did
  4. What is the scientific basis? Isn't it true that this claim has not been verified true by science?
  5. What is Lp(a) and why is it important?
  6. Pauling did not recommend the amino acid proline on the video, but you do. Explain?
  7. Describe the Linus Pauling Video on Heart Disease?
  8. What is the Tower Orthomolecular Heart Technology formula?
  9. I have had coronary by-pass operations, stents, etc. Is the Pauling Therapy safe for me?
  10. Are there any doctors who know about this?
  11. If Doctors know, why would they keep it secret?
  12. What is the difference between the Pauling Therapy and Chelation Therapy ?
  13. Why are you so against using radiation to stem restenosis (plaque regrowth).
  14. I contacted the Linus Pauling Institute. They know nothing about this. Why?

  1. Take Our Quiz! Compute your Pauling Therapy requirement.

    • Question:

      What is the scientific basis? Isn't it true that this claim has not been verified true by science?

    • Answer:

      Actually, everything we know about this is based on science. The discovery of the vital nutrients was one of the great scientific pursuits of the early twentieth century. The discovery of vitamin after vitamin wiped out the many deficiency diseases such as scurvy, beriberi and pellagra.

      Canadian medical doctors, Willis and Paterson, as early as the 1940s and 1950s during a period when scientific interest in the vitamins (especially vitamin C) was running high, conducted controlled clinical experiments with animals and humans. These doctors knew the major functions of vitamin C in the body and they were able to show that the lack of vitamin C in the diet causes atherosclerosis in Guinea pigs, and that vitamin C supplements reversed atherosclerosis in human subjects. They were ignored but the science was first rate, especially for the time.

      Pauling and his associate Rath, proposed and tested their unified theory, (which is largely based on findings that led to the 1985 Nobel prize in medicine), under tightly controlled, repeatable experimental conditions with Guinea pigs. These experiments proved that low vitamin C intake causes heart disease. These results were published in peer-reviewed scientific journals.

      The truth is that while completely ignored, excellent science is behind every aspect of the Pauling claims and invention.

      Note: We submitted (under the auspices of the Vitamin C Foundation) a comprehensive proposal in 1998 to the United States National Institutes of Health Office of Alternative Medicine. Our proposal, if funded, would have fairly evaluated the Pauling claim in a clinical setting. We proposed running two tests simultaneously using two different medical doctor (principal investigators) at two different clinics. One on the East coast and the other on the West coast. It would have been hard to deny results from such a Government/NIH sponsored BI-trial. We found medical doctors willing to conduct the study. However, we were turned down by the U. S. Government - twice.

      Intelisoft Multimedia Inc. is willing to wager (amount negotiable) that the Pauling Therapy is the cure for cardiovascular disease. Winner take all. Terms negotiable except that the patients in the control (antagonist) group must not be taking vitamin C above the RDA or lysine. [Details]

    • Question:

      What is Lp(a) and why is it important?

    • Answer:

      Lipoprotein(a) "small a" or Lp(a) is a variant of the so called "bad" LDL cholesterol. Lp(a) is "sticky" substance in the blood that Pauling and Rath believe is the lipid that begins the process of forming atherosclerotic plaques in heart disease. The 1985 Nobel prize in medicine led to the discovery of the cholesterol binding sites. The so-called Lysine Binding Sites. We now know that it is Lp(a) and not ordinary cholesterol which binds to form plaque. There are now over 1500 mainstream studies and research reports on Lp(a).

      Pauling and Rath, knowing why and how plaques form in blood vessels invented so-called Lp(a) binding inhibitors. Their three U. S. patents explain how these non-toxic substances act as plaque solvents.

      Briefly, Lp(a) has lysine (and proline) receptors. You can think of a chemical receptor as a simple lock and key. Only one key (e.g. lysine) will fit into the lock (receptor on the Lp(a) molecule.) There may be multiple receptors on the molecule, but once they are all filled up with keys (lysine or proline) the Lp(a) molecule looses its ability to bind with any more "keys." When all the Lp(a) locks have keys, Lp(a) will no longer be able to create plaque.

      Once Linus Pauling learned that Lp(a) has receptors for lysine, he knew how to counter the atherosclerosis process chemically. His invention, the Pauling Therapy, is to increase the concentration of this essential and non-toxic amino acid (and proline) in the blood serum. Lysine and proline supplements increase the concentration of free lysine and proline in the blood. The higher the concentration of the free lysine (and proline) in the blood, the more likely it is that Lp(a) molecules will bind with this lysine, rather than the lysine strands that have been exposed by cracks in blood vessels, or the other lysine that has been attracted to the Lp(a) already attached to the blood vessel wall. According to Pauling, a high concentration of free lysine can destroy existing plaques.

      It is important to keep all this in perspective using the Pauling/Rath Unified theory. If you are not getting enough vitamin C to produce collagen, and your blood vessels are wearing down, then the Lp(a) plaque is of great benefit to you. Simply removing plaque without restoring the vein or artery to health is like tearing a scab off a wound. You do not want to remove the scab until after the tissue underneath has started healing. Your body needs sufficient vitamin C so your arteries can heal.

      The Unified Theory blames mechanical stresses (high blood pressures, stretching and bending, etc.) on the blood vessels for exposing lysine that Lp(a) is attracted to. This explains why plaque doesn't always form. Atherosclerosis is a healing process. Like a scab, plaques form after a lesion or injury to the blood vessel wall.

      There is an awesome elegance that these binding inhibitors (vitamin C/lysine) are completely non-toxic. They are also the basic building blocks of collagen. The unified theory blames poor collagen production for the entire problem of heart disease. Therefore, the Pauling Therapy not only melts plaque, but it attacks the root cause by stimulating the bodies' production of collagen.

    • Question:

      Pauling did not recommend the amino acid proline on the video, but you do. Explain?

    • Answer:

      We believe that Pauling knew about the experiments that show proline can be several fold more effective as an Lp(a) Binding Inhibitor than lysine, but if not, then this is the reason. We can only speculate why Pauling focused on lysine and did not mention proline. (Note: Pauling's associate Matthias Rath, MD, does recommend proline.)

      Here is our speculation:

      1. The Lp(a) proline binding site was discovered after the lysine binding site, and not until 1996 was proline shown to be a strong binding inhibitor by researchers at the University of Chicago. (Pauling died in August 1994.)
      2. Unlike vitamin C and lysine, which are essential, meaning we must get some in our daily diet to live, the human body can make Proline. This makes it harder to determine a safe dosage on an individual basis because each person may be making different amounts of Proline in his or her cells.

      Note: It is fascinating that the Lp(a) of the Rhesus monkey has only proline binding receptors. No lysine receptors. So only proline would be able to prevent and dissolve atherosclerotic plaques in these monkeys.

    • Question:

      Describe the Linus Pauling Video

    • Answer:

      The now famous Linus Pauling Video on Heart Disease: Unified Theory of Cause and Cure is the primary record Pauling left to us on these matters. In 1993, at age 92, Pauling was recorded speaking via satellite to a health conference in Europe from his home in Malibu.

      Linus Pauling filmed this video no doubt because he believed that early cardiovascular products being developed, and coming on to the market at that time, would be ineffective; he wanted to set the record straight. These products claim to be based on this discovery, and yet they contain much less than sufficient amounts of the key ingredients (e.g. vitamin C and lysine) to effect the cure he felt possible.

      The video is notable because Pauling, without notes, gives a one hour dissertation covering the unified theory. He begins with the 1985 Nobel prize, tells the story of vitamin C, and ends with his three case histories that are now published. These cases illustrate how high-dose lysine intervention essentially cured 3 heart patients.

      The presentation can be understood by most audiences. Health professionals or those currently suffering heart disease are the primary audience.

      Because the U. S. patents had been applied for, but not granted at the time this video was filmed, Pauling had to be somewhat circumspect. He does relate how he invented the Therapy helping a fellow scientist overcome serious heart disease.

    • Question:

      Describe the Tower Orthomolecular Heart Technology formula?

    • Answer:

      Heart Technology is a Pauling Therapy drink mix formula from Tower Orthomolecular Laboratories Corporation that provides for high oral administration of the substances recommended by Linus Pauling. Tower was formed in 1996 by a friend and contributor to the Linus Pauling Institute of Science and Medicine. The benefactor, upon viewing the Linus Pauling video on Heart Disease, looked for a product already on the market that provided the high amounts of vitamin C and lysine and other nutrients recommended by Pauling. Most products offered very small amounts. Bottom Line: the only way one could obtain Pauling's recommended amounts in existing products was by consuming lots of pills. Perhaps 20-25 or more pills daily, or by mixing several unsweetened powders in juice.

      The Tower founder invented his pleasant tasting drink formula for his own personal use and subsequently formed the Tower the company to manufacture and distribute Heart Technology.

      Heart Technology combines many ingredients recommended by Linus Pauling on the video, with those previously published in HOW TO LIVE LONGER AND FEEL BETTER, into a single product that resembles Tang. (Tang is a drink mix developed for NASA.) The Tower formula includes proline, carnitine, Co-Q10, Vitamin E and Vitamin A along with vitamin C and lysine. Taste is enhanced by the herb Stevia, and for what ever reason, together in this formula, the anecdotal results have been outstanding. While a newnecdotal reports are highly encouraging, we think the objective before and after Lp(a) measurements are convincing. Lp(a) drops in many people, and it isn't supposed to. (Warren Levin, MD) We are investigating whether these results, at high dosage, can be repeated.

      It is interesting that Linus Pauling himself alerted Tower's founder to the "Lp(a)" threat during a day the two spent at Pauling's Malibu ranch in the early 1990s. Pauling mentioned the experiments that were on-going and said that if the experiments panned out, it would mean that "heart disease could be eradicated." And yes, those experiments did pan out as published in the Proceedings of the National Academy of Science.

      Information on Heart Technology and 24 Hour on-line ordering

    • Question:

      I have had coronary by-pass operations, angioplasty, stents, etc. Is the Pauling Therapy safe for me?

    • Answer:

      We are not doctors and it is safe to say that nobody really knows. But we believe the Pauling Therapy is safe based on the experience of many people in your condition who have contacted us since 1995.

      There is compelling evidence that heart by-pass, and even angioplasty are very dangerous. Neither procedure was proven before being adopted by the medical profession (Julian Whitaker, Health and Healing). No doubt these procedures have saved lives, but over the past six years we have noticed an abnormally high percentage of patients experiencing a stroke within one week of heart surgery. Many die. We are not aware of any problems with the patients who have adopted, and maintain the Pauling Therapy. (We have heard of relapses, but so far in every case, the person stopped the Pauling Therapy, perhaps due to expense or because they were feeling so good.)

      Stents worried us, but many people with stents implanted have started Heart Technology, seen their Lp(a) reduced, and tell us that in their opinion, a "miracle" has happened. They have become well. See Testimonials

      Before your doctor inserts a stent, ask him or her about the recurrence of plaque with the stent. We believe that Restenosis is higher than it would be without the stent. This is predicted by the Pauling/Rath Theory.

      It is our strong recommendation that you get well using the Pauling Therapy before stents become necessary.

      Note, if the Pauling theory is correct, it would be dangerous for any heart patient to limit vitamin C and lysine in their diet. Sufficient supplies of these nutrients promote collagen production and healing of the arteries.

    • Question:

      Are there any doctors who know about this?

    • Answer:

      A few. We maintain a referral list of Lp(a) knowledgeable physicians at this web site. We also recommend The Academy for the Advancement in Medicine web site. You can search ACAM for enlightened doctors in your area by zipcode. I would not expect ordinary medical doctors to be receptive to these ideas. It is bizarre that this could be true and not widely known or publicized.

    • Question:

      If Doctors know, why do they keep it secret?

    • Answer:

      Again, not all doctors know. Cardiologists are even TAUGHT (and probably believe) that there is no "proven" value in supplemental vitamin C for heart patients. (Of course, there is no proof vitamin C doesn't work. There is simply no proof. It has not been investigated.)

      Observation 1: There has been an enormous collective effort and combined intellect of medical researchers working on the great problem of heart disease, yet CVD remains the top killer in the USA. (Obviously this research has been headed down wrong paths, but it is hard to believe that all these people have overlooked the Vitamin C Connection to heart disease. Ignorance perpetuates itself.)

      Observation 2: a) Doctors and CEOs of pharmaceutical companies are generally smart people and b) Doctors, hospitals and pharmaceutical companies, in general, do not make a penny on people who are healthy and feeling well. (We think Doctors and Pharmacuetical companies have figured this out.)

    • Question:

      What is the difference between the Pauling Therapy and Chelation Therapy

    • Answer:

      Most of the doctors who know about and use the Pauling Therapy are doctors that utilize EDTA Chelation therapy. Chelation therapy is a means to reduce calcified plaque deposits using an IV drip. Metals (and it is thought calcium) attach to the EDTA and are expelled in the urine. Chelation Therapy has many benefits other than heart disease and is safe and approved by the FDA for the removal of heavy metals and other toxins. We suggest the excellent book FORTY SOMETHING FOREVER: A Consumers Guide To Chelation Therapy, by Arline Brecher for an excellent introduction to the many uses of IV EDTA Chelation Therapy.

      Vitamin C (and possibly lysine) can be added to the IV Chelation drip, and many doctors do add the Pauling Therapy. If you are getting Chelation, you should insist on vitamin C and lysine for the best results. Putting the Binding Inhibitors directly into the blood stream, with no loss in the gut, is probably the most powerful way to apply the Pauling therapy.

      Oral Lp(a) Binding Inhibitor products, like the Tower Orthomolecular Heart Technology formula, are ideal adjuncts to IV Chelation. They provide the nutrients that are required for healing. Maintenance doses should be used both during and after the course of IV Chelation treatment.

    • Question:

      Why are you so against using radiation to stem restenosis (plaque regrowth).

    • Answer:

      We believe that using radiation particles inside arteries to stop the regrowth of plaque is at best unethical, and at worst criminal. We hope this research is based on ignorance. If Pauling is correct, these procedures are unnecessary. The people who are subjected to radiation will not be able to heal normally and they will likely suffer a premature death. If the patients live, it is unknown what kind of dangerous side effects that radiation may itself cause (e.g. cancer.)

      Since this procedure is being studied, it is strong evidence that cardiovascular doctors are entirely ignorant of the nature and true cause of heart disease. Cardiologists have no idea that heart disease is chronic scurvy, and that plaque growth is a simple natural healing process. When they cut (by pass) or damage the arteries (angioplasty) they are surprised that the scab (atherosclerotic plaques) reforms.

      To the extent the radiation interferes with that arterial wall's ability to heal normally, such treatments make success from Pauling's cure impossible. (The Pauling therapy relies on the artery healing itself.) And although hard to believe, maybe this is the idea? Keep heart patients ill in order to perpetuate a lucrative income stream.